What is Vanadyl Sulfate?

by Dr. Julian Whitaker
Filed Under: Nutrient Guide, Nutritional Support
Last Reviewed 02/14/2014

What is Vanadyl Sulfate?

Vanadyl sulfate is a stable, inorganic form of vanadium, a unique trace mineral found in foods such as mushrooms and shellfish. Vanadium is thought to play a role in the formation of bones and teeth.

As a nutritional supplement, vanadyl sulfate is one of the safest and most effective natural therapies for diabetes and insulin resistance.

How Does Vanadyl Sulfate Work?

Vanadyl sulfate has an insulin-like effect in the body, stimulating glucose uptake and its oxidation in the cells. That’s why it is such an effective therapy for diabetes and insulin resistance. More specifically, in average doses of 100–150 mg, it has been shown to:

  • Increase insulin sensitivity
  • Lower blood sugar
  • Lower hemoglobin A1c
  • Reduce insulin requirements in people with type 1 diabetes

In studies in which cholesterol was measured, vanadyl sulfate also lowered LDL cholesterol. This is another important benefit for people with type 2 diabetes, since they are at greater risk of heart disease.

What Does the Research Say About Vanadyl Sulfate?

There are hundreds of studies—some dating back more than 20 years—that demonstrate vanadyl sulfate’s profound benefits for managing diabetes and controlling blood sugar. Here are a couple of examples:

  • In one study, eight people with type 2 diabetes received 50 mg of vanadyl sulfate twice a day for four weeks, followed by a placebo for four weeks. They were found to have a 20 percent reduction in average fasting blood sugar, which lasted well into the placebo period after the mineral was discontinued.
  • In another study, patients received 100 mg of vanadyl sulfate for three weeks. Overall, patients experienced less insulin resistance and greater glucose uptake.

What Conditions Is Vanadyl Sulfate Good For?

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